Inter- and Intra-Hemispheric Fibers of Olfactory and Motor Areas in Kallmann Syndrome with Defective Corpus Callosum
نویسندگان
چکیده
Yuri Masaoka1,2*, Andrew Zalesky2, Masaru Tatsuno3, Shingo Okamoto4, Masaki Yoshida5, Nobuyoshi Koiwa6, Mutsutaka Kobayakawa7, Keiko Watanabe1, Masahiro Ida8, Ikuo Homma9, Masahiko Izumizaki1 and Christos Pantelis2 1Department of Physiology, Showa University School of Medicine, Tokyo, Japan 2Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Melbourne, VIC, Australia 3Department of Pediatrics, Showa University School of Medicine, Tokyo, Japan 4Okamoto Children’s Clinic, Nara, Japan 5Department of Ophthalmology, Jikei Medical University, Tokyo, Japan 6Department of Health and Science, University of Human Arts and Sciences, Saitama, Japan 7Tokyo University of Information Science, Tokyo, Japan 8Department of Radiology, Stroke Center, Ebara Tokyo Hospital 9Tokyo Ariake University of Medical and Health Sciences, Tokyo, Japan
منابع مشابه
Myelin enhancement of Multiple sclerosis model with gold nanoparticles into the corpus callosum
Objective(s): With no substantial cost, we injected L-arginine into the rat’s corpus callosum (CC) to create animal model of multiple sclerosis (MS) and investigated the pre-injection effect of gold nanoparticles (GNPs). Materials and Methods: Adult male Wistar rat (250-300 g) was surgically cannulated at the CC, and after recovery it was injected L-arginine (3-200 µg/rat, intra-CC) once ...
متن کاملInter-hemispheric wave propagation failures in traumatic brain injury are indicative of callosal damage
Approximately 3.2-5.3 million Americans live with the consequences of a traumatic brain injury (TBI), making TBI one of the most common causes of disability in the world. Visual deficits often accompany TBI but physiological and anatomical evidence for injury in mild TBI is lacking. Axons traversing the corpus callosum are particularly vulnerable to TBI. Hemifield representations of early visua...
متن کاملThe anatomy of the callosal and visual-association pathways in high-functioning autism: a DTI tractography study.
There is increasing recognition that many of the core behavioral impairments that characterize autism potentially emerge from poor neural synchronization across nodes comprising dispersed cortical networks. A likely candidate for the source of this atypical functional connectivity in autism is an alteration in the structural integrity of intra- and inter-hemispheric white matter (WM) tracts tha...
متن کاملBrain changes in Kallmann syndrome.
BACKGROUND AND PURPOSE Kallmann syndrome is a rare inherited disorder due to defective intrauterine migration of olfactory axons and gonadotropin-releasing hormone neurons, leading to rhinencephalon hypoplasia and hypogonadotropic hypogonadism. Concomitant brain developmental abnormalities have been described. Our aim was to investigate Kallmann syndrome-related brain changes with conventional ...
متن کاملBrain asymmetry in the white matter making and globularity
Recent studies from the field of language genetics and evolutionary anthropology have put forward the hypothesis that the emergence of our species-specific brain is to be understood not in terms of size, but in light of developmental changes that gave rise to a more globular braincase configuration after the split from Neanderthals-Denisovans. On the grounds that (i) white matter myelination is...
متن کامل